87 ANTIOXIDANT THERAPY IN MALE INFERTILITY TREATMENT
نویسندگان
چکیده
منابع مشابه
Antioxidant therapy in male infertility: fact or fiction?
Infertile men have higher levels of semen reactive oxygen species (ROS) than do fertile men. High levels of semen ROS can cause sperm dysfunction, sperm DNA damage and reduced male reproductive potential. This observation has led clinicians to treat infertile men with antioxidant supplements. The purpose of this article is to discuss the rationale for antioxidant therapy in infertile men and to...
متن کاملThe role of antioxidant therapy in the treatment of male infertility.
Oxidative stress contributes to defective spermatogenesis leading to male factor infertility. The aim of this study was to review the current literature on the effects of various antioxidants to improve fertilisation and pregnancy rates. The sources of literature were Pubmed and the Cochrane data base. Reviewing the current literature revealed that Carnitines and vitamin C and E have been clear...
متن کاملThe role of antioxidant therapy in the treatment of male infertility: an overview.
In recent years, many studies have focused on the effect of oxidative stress, reactive oxygen species (ROS) and antioxidants on the male eproductive system. Under physiological conditions, sperm produces small amounts of ROS, which are needed for fertilisation, acrosome reaction and capacitation. However, if an increased production of ROS is not associated with a similar increase in scavenging ...
متن کاملAntioxidant treatment a new therapeutic approach to reversible male infertility
The imbalance between reactive oxygen species (ROS) production and total antioxidant capacity in seminal fluid indicates oxidative stress and is correlated with male infertility. One of the rational strategies to counteract the oxidative stress is to increase the scavenging capacity of seminal plasma. In such cases a combination of antioxidants may e more useful treatment of male infertility. W...
متن کاملVariations in Antioxidant Genes and Male Infertility
Oxidative stress and reactive oxygen species (ROS) are generated from both endogenous and environmental resources, which in turn may cause defective spermatogenesis and male infertility. Antioxidant genes, which include catalase (CAT), glutathione peroxidase (GPX), glutathione S-transferase (GST), nitric oxide synthase (NOS), nuclear factor erythroid 2-related factor 2 (NRF2), and superoxide di...
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ژورنال
عنوان ژورنال: Reproductive BioMedicine Online
سال: 2010
ISSN: 1472-6483
DOI: 10.1016/s1472-6483(10)62505-9